Each year, 700 000 people worldwide are killed by multi-resistant bacteria – microbes which cannot be wiped out by any antibiotic. According to a recent study, this death toll could rise by factor ten until the year 2050: without powerful agents up to 10 million people could die each year due to such superbugs. The film tells us how we got there: It is a story about how negligence, greed, and short-sightedness have rendered the lifesaving effects of antibiotics powerless. It is a science-thriller about disillusioned, fighting doctors, rebellious scientists, patients wrestling with life-threatening diseases and diplomats searching for a global solution.